Animal Parasitic Nematodes

ascaris

A comprehensive portfolio of assays for anthelmintics.

Parasitic nematodes infect humans, livestock and companion animals and they are a major cause of disease for human and veterinary medicine. We have an extensive track record in pharmacological analysis of parasitic nematodes and methods for investigating the physiology and behaviour of these parasites. Anthelmintic drugs used to treat these infections are becoming less effective due to the emergence of nematodes that are resistant: There is an increasing need for new compounds with novel modes of action.

We can provide:

  • Bioassays on parasitic nematodes (electrophysiological and pharmacological).
  • Mode of action studies deploying ‘model-hopping’ with C. elegans.
  • Selective toxicity assays.

See article about SLO-1-Channels of Parasitic Nematodes

Parasitic nematodes infect humans, livestock and companion animals and they are a major cause of disease for human and veterinary medicine. We have an extensive track record in pharmacological analysis of parasitic nematodes and methods for investigating the physiology and behaviour of these parasites. This incorporates ‘model-hopping’ with C. elegans to address mode of action and selective toxicity questions.

See article about SLO-1-Channels of Parasitic Nematodes